4 edition of Aging in Non-Human Primates (Interdisciplinary Topics in Gerontology) found in the catalog.
by S. Karger Publishers (USA)
Written in English
|Contributions||J. Erwin (Editor), Patrick R. Hof (Editor)|
|The Physical Object|
|Number of Pages||239|
Alternatives to the use of non-human primates (NHPs) in research and testing do exist and can complement but not yet completely replace testing on these primates. As far as possible, the number of animals used should be reduced, methodologies should be refined, and the use of animals should be replaced by alternative methods (3Rs principle). Experiments on non-human primates (NHPs) are highly controversial. Opinion polls consistently show that members of the public are particularly troubled by the practice (1–4), with many only sup-porting it with important caveats, or indeed oppos-ing it outright. A recent MORI poll in the UK found that only 16% of respondents supported the use of.
The use of non-human primates continues to be one the most contentious areas of biological and medical research. The publication of this independent report into the scientific basis for the past, current and future role of non-human primates in research is both a necessary and timely contribution to the Size: 2MB. Well, mice are mammals so I'm assuming you mean studies on non-human primates. If so, the only thing that has ever worked in an NHP model is calorie restriction. That doesn't mean other things wouldn't work, just that it hasn't been done (to my knowledge).
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on. Experiments on non-human primates have brought about important advances in biology and es often play a crucial role in the safety testing of new drugs and in research aimed at understanding how the brain works and how to prevent infectious diseases in humans.. Worldwide, more than primates are used each year for biomedical animal experimentation: over half in .
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Nonhuman primates share similar physiology and a close phylogenetic relationship to humans. The use of nonhuman primates in comparative experimental studies thus contributes to our knowledge about aging processes and translation of applications for improving health span in humans and other by: The present volume focuses on primate aging because human characteristics that evolved during their evolution are homologous with those of other primates.
Aging in Non-Human Primates book, the research on nonhuman primates will decidedly also contribute to our understanding of the process of human : J.M. Erwin. COVID Resources.
Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.
The Brain of the Aging Baboon: A Nonhuman Primate Model for Neuronal and Glial Tau Pathology --Comparative Neuropathology of Brain Aging in Primates --The Aged Rhesus Macaque in Neuroscience Research: Importance of the Nonhuman Primate Model --The Rhesus Monkey Model as a Heuristic Resource in Cognitive Aging Research --Comparative Models of.
Obesity, the metabolic syndrome, and aging share several pathogenic features in both humans and non-human primates, including insulin resistance and inflammation. The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research.
The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management.
Aging in Nonhuman Primates by P. Hof,available at Book Depository with free delivery worldwide. Information for Authors. Unique Aims and Scope. Aging publishes high-impact research papers of general interest and biological significance in all fields of aging research including but not limited to cellular senescence, organismal aging, age-related diseases, DNA damage response and repair, genetic control of aging from yeast to mammals, regulation of longevity, evolution of aging, anti.
Purchase Conn's Handbook of Models for Human Aging - 2nd Edition. Print Book & E-Book. ISBNNutrition, metabolism, and targeting aging in nonhuman primates Article in Ageing research reviews 39 February with 31 Reads How we measure 'reads'.
Alzheimer's Dementia Drug Discovery: Targeting Synaptic Glutamate Uptake A Transgenic Monkey Model of Huntington’s Disease Parkinson’s Disease in Humans and in Non-Human Primate Aging and Neurotoxin Models Genetic Models of Parkinson’s Disease and Their Study in Non-Human Primates Format: NOOK Book (Ebook).
Introduction. Both theoretical and practical reasons exist for developing a small nonhuman primate model for aging research (a fuller treatment of the logic of selection of animal models for aging research may be found in Sprott and Austad ).Conceptually, the issue is evolutionary propinquity to Cited by: 1.
ILAR J. ;52(1) Calorie restriction and aging in nonhuman primates. Kemnitz JW(1). Author information: (1)Wisconsin National Primate Research Center, Capitol Court, Madison, WIUSA. [email protected] In the 75 years since the seminal observation of Clive McCay that restriction of calorie intake extends the lifespan of rats, a great deal has been learned Cited by: Non-Human Primate Resources for Aging Research.
National Institute on Aging Office of Biological Resources and Resource Development. Contact: Nancy L.
Nadon, Ph.D. Head, Office of Biological Resources and Resource Development National Institute on Aging Wisconsin Ave., GW 2C Bethesda MD FAX [email protected] Non-human primates replicate the human aging process.
• Rhesus monkeys are a well characterized and extremely useful aging model. • The common marmoset is a developing aging model that holds great promise. • Resources exist to assist those wanting to use non-human primate aging by: Despite Long Lives, Humans Age Like Other Primates Some scientists believe humans age more slowly than other primates, judging by the exceptionally long human lifespan.
But a. A primate (/ ˈ p r aɪ m eɪ t / PRY-mayt) (from Latin primat- from primus: "prime, first rank") is a eutherian mammal constituting the taxonomic order es arose 85–55 million years ago first from small terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment Class: Mammalia.
Abstract. Among the many behavioral impairments that develop in the elderly (i.e., disturbances in cognition, affect, psychomotor function, sleep, sexual function), loss of cognitive function is generally recognized as one of the most severe and consistent dysfunctions (Weinberg, ).Cited by: Calorie Restriction and Aging in Nonhuman Primates.
Vol Number 1 67 made between them in Table 1, which summarizes the gen-eral characteristics of the animals discussed in this review.
The use of macaques in these studies does present cer. Atherosclerosis is a major age-related process and public health problem and its clinical manifestations (coronary heart disease [CHD] and cerebrovascular disease) continue to be responsible for approximately 50% of all deaths occurring annually.
In addition, CHD is responsible for over 70 to 80% of deaths among men and women over 65 years old. As our population ages (35 million people over Cited by:. First, primates have excellent have forward-facing eyes that sit close together, which allows the eyes’ fields of view to overlap and create stereoscopic, or 3-D, : Erin Wayman.The behavior and mental processes, both human and non-human, can be described through animal cognition, ethology, evolutionary psychology, and comparative psychology as well.
Human ecology is an academic discipline that investigates how humans and human societies interact with both their natural environment and the human social : Mammalia.Non-Human Primates Paperback – See all formats and editions Hide other formats and editions. Price New from Used from Paperback, "Please retry" — — — Paperback Manufacturer: Msyfield Publishing Co.,